Comparing Treatment Options



  The VNUS Closure™ Procedure Endovenous Laser Vein Stripping & Ligation
Method of action Collagen contraction resulting in a fibrotic seal1 Boiling of blood resulting in a thrombotic occlusion2 Surgical removal
Multi-center registry 97.4% closure at 1 year3 None No multi-center studies
Post-operative bruising 4%4
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2%5
38%4
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19%5
Return to normal activities within 24 hours 89.1% of patients6
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80.5% of patients5
69.8% of patients6
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46.9% of patients5

* These results were obtained using the VNUS Closure™ and ClosurePLUS™ RF products with expandable electrodes.

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1. Pichot O, et al. Role of duplex imaging in endovenous obliteration for primary venous insufficiency. J Endovasc Ther. 2000;7:451–9.
2. Proebstle TM, et al. Endovenous treatment of the greater saphenous vein with a 940 nm diode laser: thrombotic occlusion after endoluminal thermal damage by laser generated steam bubbles. J Vasc Surg. 2002;35:729–736.
3. Dietzek A, Two-Year Follow-Up Data From A Prospective, Multicenter Study Of The Efficacy Of The ClosureFAST Catheter, 35th Annual Veith Symposium. November 19, 2008. New York.
4. Morrison, N. Poster presented at American Venous Forum Meeting, February 2003.
5. Lurie F, et al. Prospective Randomized Study of Endovenous Radiofrequency Obliteration (Closure) Versus Ligation and Vein Stripping (EVOLVeS). J Vasc Surg. 2003;38:207–14.
6. Morrison N. Presented at the Union Internationale de Phlebologie, Rome, September 2001.

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